Use este identificador para citar ou linkar para este item:
http://repositorio.ufla.br/jspui/handle/1/57759
Registro completo de metadados
Campo DC | Valor | Idioma |
---|---|---|
dc.creator | Dorneles, Elaine M. S. | - |
dc.creator | Teixeira-Carvalho, Andréa | - |
dc.creator | Araújo, Márcio S. S. | - |
dc.creator | Lima, Graciela Kunrath | - |
dc.creator | Martins-Filho, Olindo O. | - |
dc.creator | Sriranganathan, Nammalwar | - |
dc.creator | Lage, Andrey P. | - |
dc.date.accessioned | 2018-02-23T13:02:47Z | - |
dc.date.accessioned | 2023-06-27T19:56:51Z | - |
dc.date.available | 2018-02-23T13:02:47Z | - |
dc.date.available | 2023-06-27T19:56:51Z | - |
dc.identifier.citation | DORNELES, E. M. S. et al. T lymphocytes subsets and cytokine pattern induced by vaccination against bovine brucellosis employing S19 calfhood vaccination and adult RB51 revaccination. Vaccine, Kidlinton, v. 32, n. 46, p. 6034-6038, 21 Oct. 2014. | pt_BR |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0264410X14012183?via%3Dihub | pt_BR |
dc.identifier.uri | http://repositorio.ufla.br/jspui/handle/1/57759 | - |
dc.description.abstract | The aims of this study were to address the protective immune response induced by S19 vaccination (n = 10) and RB51 revaccination, in pregnant (n = 9) and non-pregnant (n = 10) S19 calfhood-vaccinated cattle as follows: evaluate the in vitro CD4+ and CD8+ T-lymphocytes specific proliferation, and in vitro expression of IFN-γ by CD4+ and CD8+ T-cells and IL-4 by CD4+, CD8+ and CD21+ lymphocytes subset. Upon in vitro stimulation with γ-irradiated Brucella abortus 2308, blood mononuclear cells from S19 vaccinated and RB51 revaccinated cows exhibited significantly higher proliferation of CD4+ and CD8+ T-lymphocytes and CD4+IFN-γ+ T-cells compared to non-vaccinated animals. RB51 revaccination, regardless of the pregnancy status, did not enhance the proliferation of CD4+ or CD8+ T-cells nor IFN-γ or IL-4 production. Data from the present study suggest that cattle's cellular immune response induced after brucellosis vaccination and revaccination is due to CD4+ and CD8+ T-lymphocytes, being CD4+ T-cells the main source of IFN-γ. | pt_BR |
dc.language | en_US | pt_BR |
dc.publisher | Elsevier | pt_BR |
dc.rights | restrictAccess | pt_BR |
dc.source | Vaccine | pt_BR |
dc.subject | Calfhood vaccination | pt_BR |
dc.subject | Revaccination of pregnant cattle | pt_BR |
dc.subject | Cellular immunity | pt_BR |
dc.subject | Brucellosis | pt_BR |
dc.subject | Vacinação | pt_BR |
dc.subject | Revacinação de gado prenhes | pt_BR |
dc.title | T lymphocytes subsets and cytokine pattern induced by vaccination against bovine brucellosis employing S19 calfhood vaccination and adult RB51 revaccination | pt_BR |
dc.type | Artigo | pt_BR |
Aparece nas coleções: | DMV - Artigos publicados em periódicos |
Arquivos associados a este item:
Não existem arquivos associados a este item.
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.