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http://repositorio.ufla.br/jspui/handle/1/46660| Title: | Evaluation of genome similarities using independent components |
| Keywords: | GC-content Mycobacterium tuberculosis genomes Cluster analysis Genomas de Mycobacterium tuberculosis Análise de cluster |
| Issue Date: | 2020 |
| Publisher: | Universidade Federal de Lavras |
| Citation: | SÁFADI, T.; FERREIRA, L. M. Evaluation of genome similarities using independent components. Revista Brasileira de Biometria, Lavras, v. 38, n. 1, p. 92-101, 2020. |
| Abstract: | We propose the use of independent component analysis to find similarities of genomes. Considering different numbers of independent components, the complete linkage method was used to identify groups based on the estimated coefficients of the mixing matrix. The sequences analyzed correspond to the strains of the Mycobacterium tuberculosis genome, ten sequences were analyzed, obtained from the National Center for Biotechnology Information (NCBI, 2017). The GC-content of each sequence was evaluated using a sliding window of 10,000 bases. The clustering analysis using the independent components of the analyzed sequences was essential to verify the dissimilarity of the sequences. |
| URI: | http://repositorio.ufla.br/jspui/handle/1/46660 |
| Appears in Collections: | DES - Artigos publicados em periódicos DEX - Artigos publicados em periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ARTIGO_Evaluation of genome similarities using independent components.pdf | 299,76 kB | Adobe PDF | View/Open |
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