Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/38189
Title: Abordagem bayesiana da sensitividade de modelos para o coeficiente de endogamia
Other Titles: Bayesian approach to sensitivity of models for inbreeding coefficient
Keywords: Fator de Bayes
Desequilíbrio de Hardy-Weinberg
Simulação de dados
Bayes factor
Hardy-Weinberg disequilibrium
Data simulation
Issue Date: Sep-2009
Publisher: Universidade Federal de Santa Maria
Citation: REIS, R. L. dos; MUNIZ, J. A.; SILVA, F. F.; SÁFADI, T.; AQUINO, L. H. de. Abordagem bayesiana da sensitividade de modelos para o coeficiente de endogamia. Ciência Rural, Santa Maria, v. 39, n. 6, p. 1752-1759, set. 2009.
Abstract: The aim of this research is to perform a Bayesian characterization of the Hardy-Weinberg disequilibrium through the Bayes factor. The methodology is tested by using both simulation study and actual data. It was used the following priors for the Bayesian models: Dirichlet (model 1), beta - step uniform function (model 2), uniform - step uniform function (model 3) and independent uniforms for the inbreeding coefficients and allele frequencies (model 4). Metropolis-Hasting algorithms were implemented using the software R to simulate multiple draws from the posterior distribution. Convergence of the Metropolis-Hasting algorithms was assessed by many methods available at R package BOA. Results showed that the model 1 presents the best performance for both simulation study and actual data. The results also showed that the Bayesian approach provides models that are useful for the analysis of the Hardy-Weinberg disequilibrium and inbreeding coefficient.
URI: http://repositorio.ufla.br/jspui/handle/1/38189
Appears in Collections:DEX - Artigos publicados em periódicos

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