Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/29314
Title: Quality improvement initiatives in sepsis in an emerging country: does the institution’s main source of income influence the results? an analysis of 21,103 patients
Keywords: Sepsis - Diagnosis
Sepsis - Therapy
Public institutions - Brazil - Case studies
Private institutions - Brazil - Case studies
Hospitals - Brazil - Health programs
Issue Date: Oct-2017
Publisher: Society of Critical Care Medicine
Citation: MACHADO, F. R. et al. Quality improvement initiatives in sepsis in an emerging country: does the institution’s main source of income influence the results? an analysis of 21,103 patients. Critical Care Medicine, [S.l.], v. 45, n. 10, p. 1650–1659, Oct. 2017.
Abstract: Objective: we aimed to assess the results of a quality improvement initiative in sepsis in an emerging setting and to analyze it according to the institutions’ main source of income (public or private). Design: retrospective analysis of the Latin American Sepsis Institute database from 2005 to 2014. Settings: brazilian public and private institutions. Patients: patients with sepsis admitted in the participant institutions. Interventions: the quality improvement initiative was based on a multifaceted intervention. The institutions were instructed to collect data on 6-hour bundle compliance and outcomes in patients with sepsis in all hospital settings. Outcomes and compliance was measured for eight periods of 6 months each, starting at the time of the enrollment in the intervention. The primary outcomes were hospital mortality and compliance with 6-hour bundle. Measurements and main results: we included 21,103 patients; 9,032 from public institutions and 12,071 from private institutions. Comparing the first period with the eigth period, compliance with the 6-hour bundle increased from 13.5% to 58.2% in the private institutions (p < 0.0001) and from 7.4% to 15.7% in the public institutions (p < 0.0001). Mortality rates significantly decreased throughout the program in private institutions, from 47.6% to 27.2% in the eighth period (adjusted odds ratio, 0.45; 95% CI, 0.32–0.64). However, in the public hospitals, mortality diminished significantly only in the first two periods. Conclusion: this quality improvement initiative in sepsis in an emerging country was associated with a reduction in mortality and with improved compliance with quality indicators. However, this reduction was sustained only in private institutions.
URI: https://journals.lww.com/ccmjournal/Abstract/2017/10000/Quality_Improvement_Initiatives_in_Sepsis_in_an.8.aspx
http://repositorio.ufla.br/jspui/handle/1/29314
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