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metadata.artigo.dc.title: | A hypothesis on the role of the human immune system in COVID-19 |
metadata.artigo.dc.creator: | Khashkhosha, Hind Khairi Elhadi, Muhammed |
metadata.artigo.dc.subject: | COVID-19 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Angiotensin-converting enzyme 2 (ACE2) Human immune response |
metadata.artigo.dc.publisher: | Elsevier |
metadata.artigo.dc.date.issued: | Oct-2020 |
metadata.artigo.dc.identifier.citation: | KHASHKHOSHA, H. K.; ELHADI, M. A hypothesis on the role of the human immune system in COVID-19. Medical Hypotheses, [S.l.], v. 143, Oct. 2020. |
metadata.artigo.dc.description.abstract: | The COVID-19 pandemic has not spared any continent. The disease has affected more than 7,500,000 individuals globally and killed approximately 450,000 individuals. The disease is caused by a very small virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is an enveloped single-stranded RNA virus with a spike-like structure on its envelope that can interact with the angiotensin-converting enzyme 2 (ACE2) receptor after cleavage. ACE2 receptors are present in the human lungs and other organs. SARS-CoV-2 is a new virus that belongs to the subgenus Sarbecovirus; viruses in this subgenus have spread widely in the previous years and caused outbreaks of severe acute respiratory syndromes. |
metadata.artigo.dc.identifier.uri: | https://www.sciencedirect.com/science/article/pii/S0306987720317576 http://repositorio.ufla.br/jspui/handle/1/43136 |
metadata.artigo.dc.language: | en_US |
Appears in Collections: | FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19) |
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