Is COVID-19 receiving ADE from other coronaviruses?

Tetro, Jason A.

Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/39433

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Campo DC	Valor	Idioma
dc.creator	Tetro, Jason A.	-
dc.date.accessioned	2020-03-26T17:21:49Z	-
dc.date.available	2020-03-26T17:21:49Z	-
dc.date.issued	2020-03	-
dc.identifier.citation	TETRO, J. A. Is COVID-19 receiving ADE from other coronaviruses? Microbes and Infection, v. 22, n. 2, p. 72-73, Mar. 2020.	pt_BR
dc.identifier.uri	https://www.sciencedirect.com/science/article/pii/S1286457920300344	pt_BR
dc.identifier.uri	http://repositorio.ufla.br/jspui/handle/1/39433	-
dc.description.abstract	One of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deaths. ADE also requires prior exposure to similar antigenic epitopes, presumably circulating in local viruses, making it a possible explanation for the observed geographic limitation of severe cases and deaths.	pt_BR
dc.language	en_US	pt_BR
dc.publisher	Elsevier	pt_BR
dc.rights	restrictAccess	pt_BR
dc.source	Microbes and Infection	pt_BR
dc.subject	COVID-19	pt_BR
dc.subject	Coronavirus	pt_BR
dc.subject	Antibody dependent enhancement (ADE)	pt_BR
dc.title	Is COVID-19 receiving ADE from other coronaviruses?	pt_BR
dc.type	Artigo	pt_BR
Aparece nas coleções:	FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19)

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