Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/57167
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dc.creatorSargent, Julia-
dc.creatorMuzzi, Ruthnea-
dc.creatorMukherjee, Rajat-
dc.creatorSomarathne, Sharlene-
dc.creatorSchranz, Katherine-
dc.creatorStephenson, SaHannah-
dc.creatorConnolly, David-
dc.creatorBrodbelt, David-
dc.creatorFuentes, Virginia Luis-
dc.date.accessioned2020-10-23T15:47:21Z-
dc.date.accessioned2023-06-27T18:11:32Z-
dc.date.available2020-10-23T15:47:21Z-
dc.date.available2023-06-27T18:11:32Z-
dc.date.issued2015-03-
dc.identifier.citationSARGENT, J. et al. Echocardiographic predictors of survival in dogs with myxomatous mitral valve disease. Journal of Veterinary Cardiology, [S.l.], v. 17, n. 1, p. 1-12, Mar. 2015. DOI: 10.1016/j.jvc.2014.11.001.pt_BR
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/S1760273414000824pt_BR
dc.identifier.urihttp://repositorio.ufla.br/jspui/handle/1/57167-
dc.description.abstractObjectives: to evaluate vena contracta and other echocardiographic measures of myxomatous mitral valve disease (MMVD) severity in a multivariable analysis of survival in dogs. Animals: 70 dogs diagnosed with MMVD from stored echocardiographic images that met study inclusion criteria. Methods: left heart dimensions were measured as well as mitral regurgitant jet area/left atrial area (JAR), early mitral filling velocity (Evel), extent of mitral valve prolapse in right and left views (ProlR, ProlL), Prol indexed to aortic diameter (ProlR:Ao, ProlL:Ao), presence of a flail leaflet (FlailR, FlailL), and mitral regurgitation vena contracta diameter (VCR, VCL) indexed to aortic diameter (VCR:Ao, VCL:Ao). Follow-up from referring veterinarians was obtained by questionnaire or telephone to determine survival times. Inter- and intra-observer agreement was evaluated with Bland–Altman plots and weighted Kappa analysis. Survival was analyzed using Kaplan–Meier curves, logrank tests and Cox's proportional hazards. Results: logrank analysis showed VCL:Ao, VCR:Ao, FlailL, ProlR:Ao, ProlL:Ao, left ventricular internal dimension in diastole indexed to aortic diameter (LVIDD:Ao) >2.87, left atrium to aorta ratio (LA/Ao) >1.6, and Evel >1.4 m/s were predictors of cardiac mortality. In a multivariable analysis, the independent predictors of cardiac mortality were Evel >1.4 m/s [hazard ratio (HR) 5.0, 95% confidence interval (CI) 2.5–10.3], FlailL (HR 3.1, 95% CI 1.3–7.9), and ProlR:Ao (HR 2.8, 95% CI 1.3–6.3). Conclusions: echocardiographic measures of mitral regurgitation severity and mitral valve pathology provide valuable prognostic information independent of chamber enlargement in dogs with MMVD.pt_BR
dc.languageen_USpt_BR
dc.publisherElsevierpt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceJournal of Veterinary Cardiologypt_BR
dc.subjectCaninept_BR
dc.subjectEchocardiographypt_BR
dc.subjectMitral regurgitationpt_BR
dc.subjectPrognosispt_BR
dc.titleEchocardiographic predictors of survival in dogs with myxomatous mitral valve diseasept_BR
dc.typeArtigopt_BR
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