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dc.creatorQuaresma, Marcus V. L. dos Santos-
dc.creatorMelo, Camila Maria de-
dc.creatorRibeiro, Sandra Maria Lima-
dc.date.accessioned2023-04-04T17:11:51Z-
dc.date.available2023-04-04T17:11:51Z-
dc.date.issued2022-10-
dc.identifier.citationQUARESMA, M. V. L. dos S.; MELO, C. M. de; RIBEIRO, S. M. L. Effect of proteins, amino acids, and other nitrogenated supplements on the skeletal muscle mass in people living with HIV (PLWH): A systematic review. Clinical Nutrition ESPEN, [S.I.], v. 51, p. 160-173, Oct. 2022. DOI: https://doi.org/10.1016/j.clnesp.2022.07.001.pt_BR
dc.identifier.urihttps://doi.org/10.1016/j.clnesp.2022.07.001pt_BR
dc.identifier.urihttp://repositorio.ufla.br/jspui/handle/1/56497-
dc.description.abstractBackground & aims: Skeletal muscle losses (both quantitative and qualitative) and the consequent risk of sarcopenia are important issues in people living with HIV (PLWH), even when treated with antiretroviral therapies (ART). We aimed to conduct a systematic review (SR) investigating the effects of dietary interventions with proteins, amino acids, and other nitrogenated compounds on the skeletal muscle of PLWH. Methods: We searched the published literature until August 24th, 2020, including clinical trials predominantly with AIDS-free PLWH treated with ART. Results: From the 82 studies initially selected, 75 were excluded for the following reasons: nutritional interventions different from nitrogenated compounds; non-nutritional interventions; lack of information on body composition; and studies with most participants with AIDS. From the publications included (n ¼ 7), the majority were performed with small and heterogeneous samples. None of the studies included any new-generation ART or pre- or post-exposition drugs. Two studies found benefits of supplementation on muscle mass; one was performed in a very unfavorable socioeconomic setting, and the supplementation was based on food-derived substances. The other study supplemented creatine, and its benefits were found only when combined with physical exercise training and only by one of the methods of body composition analysis (DXA). Conclusions: Our results showed that nutritional interventions with proteins, amino acids, or other nitrogenated compounds could not improve the skeletal muscle mass in PLWH. Further studies are needed, with bigger sample sizes and more precise control of ART schemes.pt_BR
dc.languageenpt_BR
dc.publisherElsevier / European Society for Clinical Nutrition and Metabolismpt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceClinical Nutrition ESPENpt_BR
dc.subjectHuman Immunodeficiency Virus (HIV)pt_BR
dc.subjectSkeletal muscle masspt_BR
dc.subjectProteinspt_BR
dc.subjectAmino acidspt_BR
dc.subjectNitrogenated compoundspt_BR
dc.subjectMassa muscular esqueléticapt_BR
dc.subjectProteínaspt_BR
dc.subjectAminoácidospt_BR
dc.subjectCompostos nitrogenadospt_BR
dc.titleEffect of proteins, amino acids, and other nitrogenated supplements on the skeletal muscle mass in people living with HIV (PLWH): A systematic reviewpt_BR
dc.typeArtigopt_BR
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