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DC Field | Value | Language |
---|---|---|
dc.creator | Pacule, Horácio B. | - |
dc.creator | Vanegas, Javier A. G. | - |
dc.creator | Terra, Willian C. | - |
dc.creator | Campos, Vicente P. | - |
dc.creator | Oliveira, Denilson F. | - |
dc.date.accessioned | 2022-10-27T22:28:41Z | - |
dc.date.available | 2022-10-27T22:28:41Z | - |
dc.date.issued | 2022-10 | - |
dc.identifier.citation | PACULE, H. B. et al. (R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase. Experimental Parasitology, [S.I.], v. 241, 108359, Oct. 2022. DOI: https://doi.org/10.1016/j.exppara.2022.108359. | pt_BR |
dc.identifier.uri | https://doi.org/10.1016/j.exppara.2022.108359 | pt_BR |
dc.identifier.uri | http://repositorio.ufla.br/jspui/handle/1/55355 | - |
dc.description.abstract | To contribute to the development of new fumigant nematicides for the control of the plant-parasitic nematode Meloidogyne incognita, this study started with 31 volatile organic compounds reported as toxic to nematodes. At 500 μg/mL, α-ionone, (S)-carvone, (R)-carvone, 2-methylpropyl acetate, undecan-2-one, decan-2-one, and dodecan-2-one caused mortalities to M. incognita second-stage juveniles (J2) that were similar to those obtained with the commercial nematicides carbofuran (170 μg/mL) and fluensulfone (42.2 μg/mL). (R)-carvone, with a lethal concentration to 50% J2 (LC50) equal to 524 μg/mL, was selected for subsequent studies. When J2 were exposed to the (R)-carvone solution, the infectivity and reproduction on tomato were reduced. In the M. incognita egg hatching assay, (R)-carvone behaved like a true ovicide. When employed as a fumigant, (R)-carvone (3.9 g/L) was as efficient as the soil fumigant dazomet (0.245 g/L) in eliminating eggs of the nematode in a substrate to be used for tomato planting. According to in silico studies employing pharmacophoric searches and molecular docking, acetylcholinesterases are the target of (R)-carvone in the nematode. | pt_BR |
dc.language | en | pt_BR |
dc.publisher | Elsevier | pt_BR |
dc.rights | restrictAccess | pt_BR |
dc.source | Experimental Parasitology | pt_BR |
dc.subject | Root-knot nematode | pt_BR |
dc.subject | Computational chemistry | pt_BR |
dc.subject | Volatile organic compounds | pt_BR |
dc.subject | Molecular docking | pt_BR |
dc.subject | Tomato | pt_BR |
dc.subject | Nematoides-das-galhas | pt_BR |
dc.subject | Química computacional | pt_BR |
dc.subject | Compostos orgânicos voláteis | pt_BR |
dc.subject | Ancoragem molecular | pt_BR |
dc.subject | Tomate | pt_BR |
dc.title | (R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase | pt_BR |
dc.type | Artigo | pt_BR |
Appears in Collections: | DQI - Artigos publicados em periódicos |
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