Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/55355
Full metadata record
DC FieldValueLanguage
dc.creatorPacule, Horácio B.-
dc.creatorVanegas, Javier A. G.-
dc.creatorTerra, Willian C.-
dc.creatorCampos, Vicente P.-
dc.creatorOliveira, Denilson F.-
dc.date.accessioned2022-10-27T22:28:41Z-
dc.date.available2022-10-27T22:28:41Z-
dc.date.issued2022-10-
dc.identifier.citationPACULE, H. B. et al. (R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase. Experimental Parasitology, [S.I.], v. 241, 108359, Oct. 2022. DOI: https://doi.org/10.1016/j.exppara.2022.108359.pt_BR
dc.identifier.urihttps://doi.org/10.1016/j.exppara.2022.108359pt_BR
dc.identifier.urihttp://repositorio.ufla.br/jspui/handle/1/55355-
dc.description.abstractTo contribute to the development of new fumigant nematicides for the control of the plant-parasitic nematode Meloidogyne incognita, this study started with 31 volatile organic compounds reported as toxic to nematodes. At 500 μg/mL, α-ionone, (S)-carvone, (R)-carvone, 2-methylpropyl acetate, undecan-2-one, decan-2-one, and dodecan-2-one caused mortalities to M. incognita second-stage juveniles (J2) that were similar to those obtained with the commercial nematicides carbofuran (170 μg/mL) and fluensulfone (42.2 μg/mL). (R)-carvone, with a lethal concentration to 50% J2 (LC50) equal to 524 μg/mL, was selected for subsequent studies. When J2 were exposed to the (R)-carvone solution, the infectivity and reproduction on tomato were reduced. In the M. incognita egg hatching assay, (R)-carvone behaved like a true ovicide. When employed as a fumigant, (R)-carvone (3.9 g/L) was as efficient as the soil fumigant dazomet (0.245 g/L) in eliminating eggs of the nematode in a substrate to be used for tomato planting. According to in silico studies employing pharmacophoric searches and molecular docking, acetylcholinesterases are the target of (R)-carvone in the nematode.pt_BR
dc.languageenpt_BR
dc.publisherElsevierpt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceExperimental Parasitologypt_BR
dc.subjectRoot-knot nematodept_BR
dc.subjectComputational chemistrypt_BR
dc.subjectVolatile organic compoundspt_BR
dc.subjectMolecular dockingpt_BR
dc.subjectTomatopt_BR
dc.subjectNematoides-das-galhaspt_BR
dc.subjectQuímica computacionalpt_BR
dc.subjectCompostos orgânicos voláteispt_BR
dc.subjectAncoragem molecularpt_BR
dc.subjectTomatept_BR
dc.title(R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterasept_BR
dc.typeArtigopt_BR
Appears in Collections:DQI - Artigos publicados em periódicos

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.