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Título: | Monitoring of the action of drugs in melanoma cells by dynamic laser speckle |
Palavras-chave: | Specke patterns Dynamic laser speckle Cellular activity Colcemid Padrões de specke Mancha de laser dinâmica Atividade celular |
Data do documento: | Mai-2014 |
Editor: | SPIE |
Citação: | GONZÁLEZ-PEÑA, R. J. et al. Monitoring of the action of drugs in melanoma cells by dynamic laser speckle. Journal of Biomedical Optics, [S. l.], v. 19, n. 5, May 2014. DOI: https://doi.org/10.1117/1.JBO.19.5.057008. |
Resumo: | This work presents the development of a protocol based on the dynamic laser speckle designed to monitor the reaction of cancer cells of line MEL-RC08 to the application of the drug Colcemid in two different concentrations: 0.2 and 0.4 μg/mL . The protocol was designed using the forward scattering approach with an He-Ne laser of 632.8 nm illuminating the samples, a control, and two variations of Colcemid, being monitored along 8 h. The data were analyzed numerically in the time and in the frequency domain, and the results presented the ability of the technique to monitor the action of the drug, particularly Colcemid (0.4 μg/mL ). |
URI: | https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-19/issue-05/057008/Monitoring-of-the-action-of-drugs-in-melanoma-cells-by/10.1117/1.JBO.19.5.057008.full?SSO=1 http://repositorio.ufla.br/jspui/handle/1/45915 |
Aparece nas coleções: | DEG - Artigos publicados em periódicos |
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