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http://repositorio.ufla.br/jspui/handle/1/38335Registro completo de metadados
| Campo DC | Valor | Idioma |
|---|---|---|
| dc.creator | Souza, Sylvia D. F. | - |
| dc.creator | Franca, Carolina S. L. | - |
| dc.creator | Niculau, Edenilson S. | - |
| dc.creator | Costa, Larissa C. B. | - |
| dc.creator | Pinto, José E. B. | - |
| dc.creator | Alves, Péricles B. | - |
| dc.creator | Marçal, Rosilene M. | - |
| dc.date.accessioned | 2019-12-19T17:39:44Z | - |
| dc.date.available | 2019-12-19T17:39:44Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | SOUZA, S. D. F. et al. Antispasmodic effect of Ocimum selloi essential oil on the guinea-pig ileum. Natural Product Research, Abingdon, v. 29, n. 22, p. 2125-2128, 2015. | pt_BR |
| dc.identifier.uri | https://www.tandfonline.com/doi/full/10.1080/14786419.2014.989392 | pt_BR |
| dc.identifier.uri | http://repositorio.ufla.br/jspui/handle/1/38335 | - |
| dc.description.abstract | Ocimum selloi is an herbal species popularly used in Brazil as antispasmodic. Herein, we report the antispasmodic effect of O. selloi essential oil (OS) in segments of guinea-pig ileum. OS did not reduce the tonus of the ileum. In contrast, OS reduced the contraction induced by carbachol (100 μM), BaCl2 (0.03 M) and low- and high-K+ concentrations (25 and 60 mM, respectively). OS shifted the concentration–response curve for calcium to the right in a parallel manner. GC/MS analysis showed that OS consists mostly of methyl chavicol (97.57%). These results suggest that OS antispasmodic effect is mediated through calcium channel blockade. In addition, OS effect and mode of action could be accounted for methyl chavicol. | pt_BR |
| dc.language | en_US | pt_BR |
| dc.publisher | Taylor & Francis | pt_BR |
| dc.rights | restrictAccess | pt_BR |
| dc.source | Natural Product Research | pt_BR |
| dc.subject | Ocimum selloi | pt_BR |
| dc.subject | Spasmolytic | pt_BR |
| dc.subject | Methyl chavicol | pt_BR |
| dc.subject | Espasmolítico | pt_BR |
| dc.subject | Metil chavicol | pt_BR |
| dc.title | Antispasmodic effect of Ocimum selloi essential oil on the guinea-pig ileum | pt_BR |
| dc.type | Artigo | pt_BR |
| Aparece nas coleções: | DAG - Artigos publicados em periódicos | |
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