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Título: | Syzygium sp (Myrtaceae) extracts: inhibition of alpha amylase |
Palavras-chave: | Syzygium Amylase Gastric fluid Diabetes - Treatment Amilase Fluido gástrico Diabetes - Tratamento |
Data do documento: | 2014 |
Editor: | Science Domain |
Citação: | FREITAS, T. C. de; PEREIRA, C. A.; PEREIRA, L. L. S. Syzygium sp (Myrtaceae) extracts: inhibition of alpha amylase. European Journal of Medicinal Plants, [S. l.], v. 4, n. 1, p. 116-125, 2014. |
Resumo: | Aims: The aims of this study were: a) prepare crude extracts of commercial teas Syzygium sp by different methods (maceration, decoction and infusion) in different proportions (1:20, 1:50 and 1:100) and b) submit them the inhibition assays digestive enzyme alpha-amylase before and after exposure to a simulated gastric fluid. Place and Duration of Study: Laboratório de Bioquímica, Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triângulo Mineiro, Brazil, between August 2012 and July 2013. Methodology: Five samples of Syzygium sp teas were purchased commercially from pharmacies, drugstores and health food stores. Results: In the first step - inhibition of enzymatic extracts of the teas without simulated gastric fluid - the results showed significant inhibition of alpha-amylase (mean 92.84%, CV = 3.86%). However, when these extracts were placed in contact with the simulated gastric fluid was observed decreased inhibition of alpha – amylase, suggesting a possible reduction of hypoglycemic potential of these teas under physiological conditions. Conclusion: Aqueous extract Syzygium sp have high percentages of inhibition of the enzyme amylase, suggesting a potential hypoglycemic effect. Additional studies aiming at elucidating the chemical compounds present in the extracts of Syzygium sp using chromatographic techniques will be performed. |
URI: | http://repositorio.ufla.br/jspui/handle/1/15209 |
Aparece nas coleções: | DME - Artigos publicados em periódicos |
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ARTIGO_Syzygium sp (Myrtaceae) extracts - inhibition of alpha amylase.pdf | 258,16 kB | Adobe PDF | Visualizar/Abrir |
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